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  Model-based control in dimensional psychiatry

Voon, V., Reiter, A., Sebold, M., & Groman, S. (2017). Model-based control in dimensional psychiatry. Biological Psychiatry, 82(6), 391-400. doi:10.1016/j.biopsych.2017.04.006.

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Genre: Zeitschriftenartikel

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 Urheber:
Voon, Valerie1, 2, Autor
Reiter, Andrea3, 4, Autor           
Sebold, Miriam5, Autor
Groman, Stephanie6, Autor
Affiliations:
1Department of Psychiatry, University of Cambridge, United Kingdom, ou_persistent22              
2Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, United Kingdom, ou_persistent22              
3Lifespan Developmental Neuroscience, Department of Psychology, TU Dresden, Germany, ou_persistent22              
4Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
5Department of Psychiatry and Psychotherapy, Charité University Medicine Berlin, Germany, ou_persistent22              
6Department of Psychiatry, Yale University, New Haven, CT, USA, ou_persistent22              

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Schlagwörter: Addictions; Binge eating; Compulsivity; Computational psychiatry; Goal-directed control; Habit; Model-based control; Obsessive-compulsive disorder
 Zusammenfassung: We use parallel interacting goal-directed and habitual strategies to make our daily decisions. The arbitration between these strategies is relevant to inflexible repetitive behaviors in psychiatric disorders. Goal-directed control, also known as model-based control, is based on an affective outcome relying on a learned internal model to prospectively make decisions. In contrast, habit control, also known as model-free control, is based on an integration of previous reinforced learning autonomous of the current outcome value and is implicit and more efficient but at the cost of greater inflexibility. The concept of model-based control can be further extended into pavlovian processes. Here we describe and compare tasks that tap into these constructs and emphasize the clinical relevance and translation of these tasks in psychiatric disorders. Together, these findings highlight a role for model-based control as a transdiagnostic impairment underlying compulsive behaviors and representing a promising therapeutic target.

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Sprache(n): eng - English
 Datum: 2017-04-112016-12-142017-04-122017-04-232017-09-15
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1016/j.biopsych.2017.04.006
PMID: 28599832
Anderer: Epub 2017
 Art des Abschluß: -

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Projektname : -
Grant ID : -
Förderprogramm : Medical Research Council Senior Clinical Fellowship
Förderorganisation : Medical Research Council (MRC)
Projektname : -
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Förderprogramm : -
Förderorganisation : German Research Foundation (DFG)

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Titel: Biological Psychiatry
  Andere : Biol. Psychiatry
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: New York : Elsevier
Seiten: - Band / Heft: 82 (6) Artikelnummer: - Start- / Endseite: 391 - 400 Identifikator: ISSN: 0006-3223
CoNE: https://pure.mpg.de/cone/journals/resource/954925384111