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  The influence of vision on tactile Hebbian learning

Kuehn, E., Doehler, J., & Pleger, B. (2017). The influence of vision on tactile Hebbian learning. Scientific Reports, 7: 9069. doi:10.1038/s41598-017-09181-6.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-DE9D-2 Version Permalink: http://hdl.handle.net/21.11116/0000-0004-4D9D-6
Genre: Journal Article

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 Creators:
Kuehn, Esther1, 2, 3, Author              
Doehler, Juliane1, 4, Author
Pleger, Burkhard1, 5, Author              
Affiliations:
1Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
2Center for Behavioral Brain Sciences, Magdeburg, Germany, ou_persistent22              
3Aging and Cognition Research Group, German Center for Neurodegenerative Diseases, Magdeburg, Germany, ou_persistent22              
4Institute of Psychology, University of Leipzig, Germany, ou_persistent22              
5Department of Neurology, University Hospital Bergmannsheil, Bochum, Germany, ou_persistent22              

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 Abstract: NMDA-dependent Hebbian learning drives neuronal plasticity in different cortical areas, and across species. In the primary somatosensory cortex (S-I), Hebbian learning is induced via the persistent low-rate afferent stimulation of a small area of skin. In particular, plasticity is induced in superficial cortical layers II/III of the S-I cortex that represents the stimulated area of skin. Here, we used the model system of NMDA-dependent Hebbian learning to investigate the influence of non-afferent (visual) input on Hebbian plasticity in S-I. We induced Hebbian learning in 48 participants by applying 3 hours of tactile coactivation to the right index fingertip via small loudspeaker membranes. During coactivation, different groups viewed either touches to individual fingers, which is known to activate S-I receptive fields, touches to an object, which should not activate S-I receptive fields, or no touch at all. Our results show that coactivation significantly lowers tactile spatial discrimination thresholds at the stimulated finger post- versus pre-training across groups. However, we did not find evidence for a significant modulatory effect of visual condition on tactile spatial discrimination performance. This suggests that non-afferent (visual) signals do not interact with Hebbian learning in superficial cortical layers of S-I, but may integrate into deeper cortical layers instead.

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Language(s): eng - English
 Dates: 2017-03-292017-07-242017-08-22
 Publication Status: Published online
 Pages: -
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 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1038/s41598-017-09181-6
PMID: 28831156
PMC: PMC5567334
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Grant ID : SAS-2015_LIN_LWC
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Funding organization : CBBS ScienceCampus - Leibniz Association
Project name : Integration and Representation of Sensory Processes / SFB 874
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Funding program : -
Funding organization : Deutsche Forschungsgemeinschaft (DFG)

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Title: Scientific Reports
  Abbreviation : Sci. Rep.
Source Genre: Journal
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Publ. Info: London, UK : Nature Publishing Group
Pages: - Volume / Issue: 7 Sequence Number: 9069 Start / End Page: - Identifier: ISSN: 2045-2322
CoNE: https://pure.mpg.de/cone/journals/resource/2045-2322