English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Increased retention of calcium in the dendrites of long-term potentiated CA1 neurons of the hippocampal slice. A combined electrophysiological and electron histochemical study.

Kuhnt, U., Mihaly, A., Siklos, L., & Joo, F. (1988). Increased retention of calcium in the dendrites of long-term potentiated CA1 neurons of the hippocampal slice. A combined electrophysiological and electron histochemical study. Histochemistry, 90(3), 185-193. doi:10.1007/BF00492506.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Kuhnt, U.1, Author           
Mihaly, A.1, Author           
Siklos, L.1, Author           
Joo, F., Author
Affiliations:
1Abteilung Neurobiologie, MPI for biophysical chemistry, Max Planck Society, ou_578620              

Content

show
hide
Free keywords: -
 Abstract: In view of the importance of calcium in the induction of long-term potentiation (LTP), experiments were carried out to localize calcium at the electron microscopic level in the CA1 region of guinea pig hippocampal slices, following high-frequency stimulation of the Schaffer collaterals. Apart from the ultrastructural localization, a semi-quantitative method was used to count the calcium-containing deposits in electron micrographs. Significantly more calcium-containing deposits were seen in the dendrites of the stratum radiatum in slices with LTP than in those without it. A moderate increase of the extradendritic deposits was observed, too. The calcium content of the deposits was determined by means of EGTA incubation and X-ray analysis. The presented results, together with the relevant literature data, underline the importance of calcium-activated processes in postsynaptic structures probably involved in the generation of LTP.

Details

show
hide
Language(s): eng - English
 Dates: 1988-05
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1007/BF00492506
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Histochemistry
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 90 (3) Sequence Number: - Start / End Page: 185 - 193 Identifier: -