English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
 Local TagsRelease HistoryDetailsSummary
  In-vivo magnetic resonance imaging (MRI) of laminae in the human cortex

Trampel, R., Bazin, P.-L., Pine, K., & Weiskopf, N. (2019). In-vivo magnetic resonance imaging (MRI) of laminae in the human cortex. NeuroImage, 197, 707-715. doi:10.1016/j.neuroimage.2017.09.037.

Item is

 

show all hide all

Basic

show hide
Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002D-FD80-8 Version Permalink: https://hdl.handle.net/21.11116/0000-0005-4F78-D
Genre: Journal Article

Files

show Files
hide Files
:
Trampel_Bazin_2017.pdf (Publisher version), 3MB
View   Save
File Permalink:
https://hdl.handle.net/21.11116/0000-0001-F954-8
Name:
Trampel_Bazin_2017.pdf
Description:
-
OA-Status:
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
View
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Trampel, Robert1, Author           
Bazin, Pierre-Louis1, 2, 3, Author           
Pine, Kerrin1, Author           
Weiskopf, Nikolaus1, Author           
Affiliations:
1Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_2205649              
2Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
3Spinoza Centre for Neuroimaging, University of Amsterdam, the Netherlands, ou_persistent22              

Content

show
hide
Free keywords: Cortical layers; In-vivo histology; Laminar depth coordinate system; Stria of Gennari
 Abstract: The human neocortex is organized radially into six layers which differ in their myelination and the density and arrangement of neuronal cells. This cortical cyto- and myeloarchitecture plays a central role in the anatomical and functional neuroanatomy but is primarily accessible through invasive histology only. To overcome this limitation, several non-invasive MRI approaches have been, and are being, developed to resolve the anatomical cortical layers. As a result, recent studies on large populations and structure-function relationships at the laminar level became possible. Early proof-of-concept studies targeted conspicuous laminar structures such as the stria of Gennari in the primary visual cortex. Recent work characterized the laminar structure outside the visual cortex, investigated the relationship between laminar structure and function, and demonstrated layer-specific maturation effects. This paper reviews the methods and in-vivo MRI studies on the anatomical layers in the human cortex based on conventional and quantitative MRI (excluding diffusion imaging). A focus is on the related challenges, promises and potential future developments. The rapid development of MRI scanners, motion correction techniques, analysis methods and biophysical modeling promise to overcome the challenges of spatial resolution, precision and specificity of systematic imaging of cortical laminae.

Details

show
hide
Language(s): eng - English
 Dates: 2017-09-132017-04-142017-09-192017-09-202019-08-15
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.neuroimage.2017.09.037
PMID: 28942063
Other: Epub 2017
 Degree: -

Event

show

Legal Case

show

Project information

show hide
Project name : Non-invasive in vivo histology in health and disease using Magnetic Resonance Imaging (MRI) / HMRI
Grant ID : 616905
Funding program : FP7 (ERC-2013-CoG)
Funding organization : European Research Council (ERC)
Project name : Antibodies against Nogo-A to enhance plasticity, regeneration and functional recovery after acute spinal cord injury, a multicenter European clinical proof of concept trial /NISCI
Grant ID : 681094
Funding program : Horizon 2020 (H2020-PHC-2014-2015)
Funding organization : European Union (EU)
Project name : Talking imaging into the therapeutic domain: Self-regulation of brain systems for mental disorders / BRAINTRAIN
Grant ID : 602186
Funding program : Funding Programme 7 (FP7-HEALTH-2013-INNOVATION-1)
Funding organization : European Union (EU)
Project name : -
Grant ID : 15.0137
Funding program : -
Funding organization : Swiss State Secretariat for Education, Research and Innovation (SERI)

Source 1

show
hide
Title: NeuroImage
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Orlando, FL : Academic Press
Pages: - Volume / Issue: 197 Sequence Number: - Start / End Page: 707 - 715 Identifier: ISSN: 1053-8119
CoNE: https://pure.mpg.de/cone/journals/resource/954922650166