Deutsch
 
Benutzerhandbuch Datenschutzhinweis Impressum Kontakt
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT
  Electromechanical optical mapping

Christoph, J., Schröder-Schetelig, J., & Luther, S. (2017). Electromechanical optical mapping. Progress in Biophysics and Molecular Biology, 130, 150-169. doi:10.1016/j.pbiomolbio.2017.09.015.

Item is

Basisdaten

einblenden: ausblenden:
Datensatz-Permalink: http://hdl.handle.net/11858/00-001M-0000-002E-1312-6 Versions-Permalink: http://hdl.handle.net/21.11116/0000-0001-30B5-C
Genre: Zeitschriftenartikel

Externe Referenzen

einblenden:

Urheber

einblenden:
ausblenden:
 Urheber:
Christoph, Jan1, Autor              
Schröder-Schetelig, Johannes1, Autor              
Luther, Stefan1, Autor              
Affiliations:
1Research Group Biomedical Physics, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society, ou_2063288              

Inhalt

einblenden:
ausblenden:
Schlagwörter: Optical mapping; Cardiac fibrillation; Excitation-contraction coupling; Image registration; Motion artifact; Motion tracking
 Zusammenfassung: Optical mapping is a widely used imaging technique for investigating cardiac electrophysiology in intact, Langendorff-perfused hearts. Mechanical contraction of cardiac tissue, however, may result in severe motion artifacts and significant distortion of the fluorescence signals. Therefore, pharmacological uncoupling is widely used to reduce tissue motion. Recently, various image processing algorithms have been proposed to reduce motion artifacts. We will review these technological developments. Furthermore, we will present a novel approach for the three-dimensional, marker-free reconstruction of contracting Langendorff-perfused intact hearts under physiological conditions. The algorithm allows disentangling the fluorescence signals (e.g. membrane voltage or intracellular calcium) from the mechanical motion (e.g. tissue strain). We will discuss the algorithms reconstruction accuracy, resolution, and robustness using experimental data from Langendorff-perfused rabbit hearts.

Details

einblenden:
ausblenden:
Sprache(n): eng - Englisch
 Datum: 2017-09-222017-11
 Publikationsstatus: Im Druck publiziert
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1016/j.pbiomolbio.2017.09.015
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: Progress in Biophysics and Molecular Biology
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 130 Artikelnummer: - Start- / Endseite: 150 - 169 Identifikator: -