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  Two possible modes of pioneering associated with combinations of H2A.Z and p300/CBP at nucleosome-occupied enhancers

Cauchy, P., Koch, F., & Andrau, J.-C. (2017). Two possible modes of pioneering associated with combinations of H2A.Z and p300/CBP at nucleosome-occupied enhancers. Transcription, 8(3), 179-184. doi:10.1080/21541264.2017.1291395.

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© 2017 Taylor & Francis
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 Creators:
Cauchy, Pierre , Author
Koch, Frederic1, Author              
Andrau, Jean-Christophe , Author
Affiliations:
1Dept. of Developmental Genetics (Head: Bernhard G. Herrmann), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433548              

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Free keywords: H2A.Z; MNase-Seq; labile; nucleosome; p300/CBP; transcription factor
 Abstract: Pioneer transcription factors are defined by their ability to bind nucleosome-occupied regions. Here, we discuss the properties of nucleosomes bound by pioneers at enhancer regions. We describe how select pioneers bind nucleosome-occupied or -depleted enhancer sites. Importantly, by revisiting and expanding existing data sets, we show differential H2A.Z and p300/CBP association at bound enhancers, highlighting two possible pioneering modes.

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Language(s): eng - English
 Dates: 2017-02-132017-05-27
 Publication Status: Published in print
 Pages: 6
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 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1080/21541264.2017.1291395
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Title: Transcription
Source Genre: Journal
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Publ. Info: Taylor & Francis
Pages: - Volume / Issue: 8 (3) Sequence Number: - Start / End Page: 179 - 184 Identifier: ISSN: 2154-1264 (Print) 2154-1272 (Online)