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  Could high mental demands at work offset the adverse association between social isolation and cognitive functioning?: Results of the population-based LIFE-adult-study

Rodriguez, F. S., Schroeter, M. L., Witte, V., Engel, C., Löffler, M., Thiery, J., et al. (2017). Could high mental demands at work offset the adverse association between social isolation and cognitive functioning?: Results of the population-based LIFE-adult-study. The American Journal of Geriatric Psychiatry, 25(11), 1258-1269. doi:10.1016/j.jagp.2017.05.014.

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 Creators:
Rodriguez, Francisca S.1, 2, 3, Author
Schroeter, Matthias L.4, 5, Author           
Witte, Veronica4, 5, 6, Author           
Engel, Christoph3, 7, 8, Author
Löffler, Markus3, 7, 8, Author
Thiery, Joachim9, Author
Villringer, Arno4, 5, Author           
Luck, Tobias2, 3, Author
Riedel-Heller, Steffi G.2, Author
Affiliations:
1Edward R. Roybal Institute on Aging, University of Southern California, Los Angeles, CA, USA, ou_persistent22              
2Institute of Social Medicine, Occupational Health and Public Health (ISAP), University Hospital Leipzig, Germany, ou_persistent22              
3Leipzig Research Center for Civilization Diseases (LIFE), University of Leipzig, Germany, ou_persistent22              
4Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
5Clinic for Cognitive Neurology, University of Leipzig, Germany, ou_persistent22              
6Collaborative Research Center Obesity Mechanisms, Institute of Biochemistry, University of Leipzig, Germany, ou_persistent22              
7Faculty of Medicine, University of Leipzig, Germany, ou_persistent22              
8Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, Germany, ou_persistent22              
9Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics (ILM), University of Leipzig, Germany, ou_persistent22              

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Free keywords: Social isolation; Social network; Cognitive functioning; Mental demands; Aging
 Abstract: Objectives The study investigated whether high mental demands at work, which have shown to promote a good cognitive functioning in old age, could offset the adverse association between social isolation and cognitive functioning. Methods Based on data from the population-based LIFE-Adult-Study, the association between cognitive functioning (Verbal Fluency Test, Trail Making Test B) and social isolation (Lubben Social Network Scale) as well as mental demands at work (O*NET database) was analyzed via linear regression analyses adjusted for age, sex, education, and sampling weights. Results Cognitive functioning was significantly lower in socially isolated individuals and in individuals working in low mental demands jobs—even in old age after retirement and even after taking into account the educational level. An interaction effect suggested stronger effects of mental demands at work in socially isolated than nonisolated individuals. Conclusions The findings suggest that working in high mental-demand jobs could offset the adverse association between social isolation and cognitive functioning. Further research should evaluate how interventions that target social isolation and enhance mentally demanding activities promote a good cognitive functioning in old age.

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Language(s): eng - English
 Dates: 2017-05-152016-12-142017-05-252017-05-292017-11
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.jagp.2017.05.014
PMID: 28669574
Other: Epub 2017
 Degree: -

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Title: The American Journal of Geriatric Psychiatry
  Abbreviation : Am J Geriatr Psychiatry
Source Genre: Journal
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Publ. Info: Washington, DC : American Psychiatry Press
Pages: - Volume / Issue: 25 (11) Sequence Number: - Start / End Page: 1258 - 1269 Identifier: ISSN: 1064-7481
CoNE: https://pure.mpg.de/cone/journals/resource/1064-7481