English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Aerosol health effects from molecular to global scales.

Shiraiwa, M., Ueda, K., Pozzer, A., Lammel, G., Kampf, C. J., Fushimi, A., et al. (2017). Aerosol health effects from molecular to global scales. Environmental Science & Technology, 51(23), 13545-13567. doi:10.1021/acs.est.7b04417.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Shiraiwa, Manabu, Author
Ueda, Kayo, Author
Pozzer, Andrea1, Author              
Lammel, Gerhard2, Author              
Kampf, Christopher J.2, Author              
Fushimi, Akihiro, Author
Enami, Shinichi, Author
Arrangio , Andrea M., Author
Fröhlich-Nowoisky, Janine2, Author              
Fujitani, Yuji, Author
Furuyama, Akiko, Author
Lakey, Pascale S. J.2, Author              
Lelieveld, Jos1, Author              
Lucas, Kurt2, Author              
Morino, Yu, Author
Pöschl, Ulrich2, Author              
Takahama, Satoshi, Author
Takami, Akinori, Author
Tong, Haijie2, Author              
Weber, Bettina2, Author              
Yoshino, Ayako, AuthorSato, Kei, Author more..
Affiliations:
1Atmospheric Chemistry, Max Planck Institute for Chemistry, Max Planck Society, ou_1826285              
2Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society, ou_1826290              

Content

show
hide
Free keywords: -
 Abstract: Poor air quality is the globally largest environmental health risk. Epidemiological studies have uncovered clear relationships of gaseous pollutants and particulate matter (PM) with adverse health outcomes, including mortality by cardiovascular and respiratory diseases. Studies of health impacts by aerosols are highly multidisciplinary with a broad range of scales in space and time. We assess recent advances and future challenges regarding aerosol effects on health from molecular to global scales, through epidemiological studies, field measurements, health-related properties of PM, and multiphase interactions of oxidants and PM upon respiratory deposition. Global modeling combined with epidemiological exposure-response functions indicates that ambient air pollution causes more than four million premature deaths per year. Epidemiological studies usually refer to PM mass concentrations, but some health effects may relate to specific constituents such as bioaerosols, polycyclic aromatic compounds, and transition metals. Various analytical techniques, cellular and molecular assays are applied to assess the redox activity of PM and the formation of reactive oxygen species. Multiphase chemical interactions of lung antioxidants with atmospheric pollutants are crucial to the mechanistic and molecular understanding of oxidative stress upon respiratory deposition. The role of distinct PM components in health impacts and mortality needs to be clarified by integrated research on various spatiotemporal scales for better evaluation and mitigation of aerosol effects on public health in the Anthropocene.

Details

show
hide
Language(s): eng - English
 Dates: 2017
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1021/acs.est.7b04417
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Environmental Science & Technology
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Easton, PA : American Chemical Society
Pages: - Volume / Issue: 51 (23) Sequence Number: - Start / End Page: 13545 - 13567 Identifier: ISSN: 0013-936X
CoNE: https://pure.mpg.de/cone/journals/resource/954921342157