English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Inducing high activity of a thermophilic enzyme at ambient temperatures by directed evolution

Li, G., Maria-Solano, M. A., Romero-Rivera, A., Osuna, S., & Reetz, M. T. (2017). Inducing high activity of a thermophilic enzyme at ambient temperatures by directed evolution. Chemical Communications, 53(68), 9454-9457. doi:10.1039/C7CC05377K.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Li, Guangyue1, 2, Author              
Maria-Solano, Miguel A.3, Author
Romero-Rivera, Adrian3, Author
Osuna, Silvia3, Author
Reetz, Manfred T.1, 2, Author              
Affiliations:
1Research Department Reetz, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445588              
2Philipps-Universität Marburg, Fachbereich Chemie, ou_persistent22              
3Institut de Química Computacional i Catàlisi and Department de Química, Universitat de Girona, Carrer Maria Aurèlia Capmany 6, Girona 17003, Spain , ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: The long-standing problem of achieving high activity of a thermophilic enzyme at low temperatures and short reaction times with little tradeoff in thermostability has been solved by directed evolution, an alcohol dehydrogenase found in hot springs serving as the catalyst in enantioselective ketone reductions.

Details

show
hide
Language(s): eng - English
 Dates: 2017-08-012017-08-042017-09-04
 Publication Status: Published in print
 Pages: 4
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1039/C7CC05377K
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Chemical Communications
  Other : Chem. Commun.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cambridge, UK : Royal Society of Chemistry
Pages: - Volume / Issue: 53 (68) Sequence Number: - Start / End Page: 9454 - 9457 Identifier: ISSN: 1359-7345
CoNE: https://pure.mpg.de/cone/journals/resource/954928495413