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  Ancillary Activity: Beyond Core Metabolism in Immune Cells

Puleston, D., Mateo, V., & Pearce, E. L. (2017). Ancillary Activity: Beyond Core Metabolism in Immune Cells. Cell Metabolism, 26, 131-141. doi:10.1016/j.cmet.2017.06.019.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0000-BF69-4 Version Permalink: https://hdl.handle.net/21.11116/0000-0008-948F-0
Genre: Journal Article

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Puleston et al..pdf (Publisher version), 1005KB
 
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https://www.sciencedirect.com/science/article/pii/S1550413117303625?via%3Dihub (Publisher version)
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 Creators:
Puleston, Daniel1, 2, Author           
Mateo, Villa1, Author           
Pearce, Erika L.1, Author           
Affiliations:
1Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society, 79108 Freiburg, DE, ou_2243640              
2Nuffield Department of Orthopedics, Rheumatology, and Musculoskeletal Diseases, The Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK, ou_persistent22              

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 Abstract: Immune cell function and fate are intimately linked to engagement of metabolic pathways. The contribution of core metabolic pathways to immune cell bioenergetics has been vigorously investigated in recent years. However, precisely how other peripheral metabolic pathways support immune cells beyond energy generation is less well understood. Here we survey the literature and highlight recent advances in our understanding of several ancillary metabolic pathways and how they support processes beyond ATP production and ultimately contribute to protective immunity.

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Language(s): eng - English
 Dates: 2017-07-05
 Publication Status: Issued
 Pages: -
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 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.cmet.2017.06.019
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Title: Cell Metabolism
  Other : Cell Metabolism
Source Genre: Journal
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Publ. Info: Cambridge, MA : Cell Press
Pages: - Volume / Issue: 26 Sequence Number: - Start / End Page: 131 - 141 Identifier: ISSN: 1550-4131
CoNE: https://pure.mpg.de/cone/journals/resource/111088195284928