ausblenden:
Schlagwörter:
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Zusammenfassung:
The deficiency of robust and practical methods
for 18F-radiofluorination is a bottleneck for positron emission
tomography (PET) tracer development. Here, we report the
first transition-metal-assisted 18F-deoxyfluorination of phenols. The transformation benefits from readily available phenols as
starting materials, tolerance of moisture and ambient atmosphere, large substrate scope, and translatability to
generate doses appropriate for PET imaging.