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  Two possible modes of pioneering associated with combination of H2A.Z and p300/CBP at nucleosome-occupied enhancers

Cauchy, P., Koch, F., & Andrau, J.-C. (2017). Two possible modes of pioneering associated with combination of H2A.Z and p300/CBP at nucleosome-occupied enhancers. Transcription, 8, 179-184. doi:10.1080/21541264.2017.1291395.

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 Creators:
Cauchy, Pierre1, Author           
Koch, Frederic2, Author
Andrau, Jean-Christophe3, Author
Affiliations:
1Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society, ou_2243641              
2Max Planck Institute for Molecular Genetics, Max Planck Society, Ihnestraße 63-73, 14195 Berlin, DE, ou_1433545              
3Institut de Genetique Moleculaire de Montpellier, Montpellier, France, ou_persistent22              

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 Abstract: Pioneer transcription factors are defined by their ability to bind nucleosome-occupied regions. Here, we discuss the properties of nucleosomes bound by pioneers at enhancer regions. We describe how select pioneers bind nucleosome-occupied or -depleted enhancer sites. Importantly, by revisiting and expanding existing data sets, we show differential H2A.Z and p300/CBP association at bound enhancers, highlighting two possible pioneering modes.

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Language(s): eng - English
 Dates: 2017
 Publication Status: Issued
 Pages: -
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1080/21541264.2017.1291395
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Title: Transcription
Source Genre: Journal
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Publ. Info: Taylor & Francis
Pages: - Volume / Issue: 8 Sequence Number: - Start / End Page: 179 - 184 Identifier: -