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  Paramagnetic Lanthanide Chelates for Multicontrast MRI

Cakić, N., Savić, T., Stricker-Shaver, J., Truffault, V., Platas-Iglesias, C., Mirkes, C., et al. (2016). Paramagnetic Lanthanide Chelates for Multicontrast MRI. Chemical Communications, 52(59), 9224-9227. doi:10.1039/C6CC04011J.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0000-79A8-B Version Permalink: http://hdl.handle.net/21.11116/0000-0000-FA3E-2
Genre: Journal Article

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 Creators:
Cakić, N1, 2, Author              
Savić, T2, 3, Author              
Stricker-Shaver, J2, Author              
Truffault, V, Author
Platas-Iglesias, C, Author
Mirkes, C1, Author              
Pohmann, R1, 2, Author              
Scheffler, K1, 2, Author              
Angelovski, G2, 3, Author              
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
3Research Group MR Neuroimaging Agents, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528691              

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 Abstract: The preparation of a paramagnetic chelator that serves as platform for multicontrast MRI, and can be utilized either as a T1-weighted, paraCEST or 19F MRI contrast agent is reported. Its europium(III) complex exhibits extremely slow water exchange rate which is optimal for the use in CEST MRI. The potential of this platform was demonstrated through a series of MRI studies on tube phantoms and animals.

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 Dates: 2016-07
 Publication Status: Published in print
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 Identifiers: DOI: 10.1039/C6CC04011J
BibTex Citekey: CakiSSTPMPSA2016
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Title: Chemical Communications
Source Genre: Journal
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Pages: - Volume / Issue: 52 (59) Sequence Number: - Start / End Page: 9224 - 9227 Identifier: -