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  Triple-quantum-filtered sodium imaging at 9.4 Tesla

Mirkes, C., Shajan, G., Bause, J., Buckenmaier, K., Hoffmann, J., & Scheffler, K. (2016). Triple-quantum-filtered sodium imaging at 9.4 Tesla. Magnetic Resonance in Medicine, 75(3), 1278-1289. doi:10.1002/mrm.25688.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0000-7A12-3 Version Permalink: http://hdl.handle.net/21.11116/0000-0000-7A13-2
Genre: Journal Article

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Mirkes, C1, Author              
Shajan, G1, Author              
Bause, J1, 2, Author              
Buckenmaier, K1, 2, Author              
Hoffmann, J1, 2, Author              
Scheffler, K1, 2, Author              
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1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: Purpose Efficient acquisition of triple-quantum-filtered (TQF) sodium images at ultra-high field (UHF) strength. Methods A three-pulse preparation and a stack of double-spirals were used for the acquisition of TQF images at 9.4 Tesla. The flip angles of the TQ preparation were smoothly reduced toward the edge of k-space along the partition-encoding direction. In doing so, the specific absorption rate could be reduced while preserving the maximal signal intensity for the partitions most relevant for image contrast in the center of k-space. Simulations, phantom and in vivo measurements were used to demonstrate the usefulness of the proposed method. Results A higher sensitivity (∼20) was achieved compared to the standard acquisition without flip angle apodization. Signals from free sodium ions were successfully suppressed irrespective of the amount of apodization used. B0 corrected TQF images with a nominal resolution of 5 × 5 × 5 mm3 and an acceptable signal-to-noise ratio could be acquired in vivo within 21 min. Conclusion Conventional TQF in combination with flip angle apodization permits to exploit more efficiently the increased sensitivity available at 9.4T.

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 Dates: 2016-03
 Publication Status: Published in print
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 Identifiers: DOI: 10.1002/mrm.25688
BibTex Citekey: MirkesSBBHS2015
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Title: Magnetic Resonance in Medicine
Source Genre: Journal
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Pages: - Volume / Issue: 75 (3) Sequence Number: - Start / End Page: 1278 - 1289 Identifier: -