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  Signal-to-noise ratio and MR tissue parameters in human brain imaging at 3, 7, and 9.4 tesla using current receive coil arrays

Pohmann, R., Speck, O., & Scheffler, K. (2016). Signal-to-noise ratio and MR tissue parameters in human brain imaging at 3, 7, and 9.4 tesla using current receive coil arrays. Magnetic Resonance in Medicine, 75(2), 801-809. doi:10.1002/mrm.25677.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0000-7A32-F Version Permalink: http://hdl.handle.net/21.11116/0000-0000-FA37-9
Genre: Journal Article

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Pohmann, R1, 2, Author              
Speck, O, Author
Scheffler, K1, 2, Author              
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1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: Purpose Relaxation times, transmit homogeneity, signal-to-noise ratio (SNR) and parallel imaging g-factor were determined in the human brain at 3T, 7T, and 9.4T, using standard, tight-fitting coil arrays. Methods The same human subjects were scanned at all three field strengths, using identical sequence parameters and similar 31- or 32-channel receive coil arrays. The SNR of three-dimensional (3D) gradient echo images was determined using a multiple replica approach and corrected with measured flip angle and T2* distributions and the T1 of white matter to obtain the intrinsic SNR. The g-factor maps were derived from 3D gradient echo images with several GRAPPA accelerations. Results As expected, T1 values increased, T2* decreased and the B1-homogeneity deteriorated with increasing field. The SNR showed a distinctly supralinear increase with field strength by a factor of 3.10 ± 0.20 from 3T to 7T, and 1.76 ± 0.13 from 7T to 9.4T over the entire cerebrum. The g-factors did not show the expected decrease, indicating a dominating role of coil design. Conclusion In standard experimental conditions, SNR increased supralinearly with field strength (SNR ∼ B01.65). To take full advantage of this gain, the deteriorating B1-homogeneity and the decreasing T2* have to be overcome.

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 Dates: 2016-02
 Publication Status: Published in print
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 Identifiers: DOI: 10.1002/mrm.25677
BibTex Citekey: PohmannSS2015
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Title: Magnetic Resonance in Medicine
Source Genre: Journal
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Pages: - Volume / Issue: 75 (2) Sequence Number: - Start / End Page: 801 - 809 Identifier: -