English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  The anatomical substrate of precise timing in zebra finch HVC

Kornfeld, J., Benezra, S., Narayanan, R., Svara, F., Oberlaender, M., Denk, W., et al. (2016). The anatomical substrate of precise timing in zebra finch HVC. Poster presented at 46th Annual Meeting of the Society for Neuroscience (Neuroscience 2016), San Diego, CA, USA.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0000-7ADA-2 Version Permalink: http://hdl.handle.net/21.11116/0000-0005-E1DE-3
Genre: Poster

Files

show Files

Locators

show
hide
Locator:
Link (Any fulltext)
Description:
-

Creators

show
hide
 Creators:
Kornfeld, J, Author
Benezra, S, Author
Narayanan, RT1, 2, Author              
Svara, F, Author
Oberlaender, M1, 2, Author              
Denk, W, Author
Long, MA, Author
Affiliations:
1Former Research Group Computational Neuroanatomy, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528698              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

Content

show
hide
Free keywords: -
 Abstract: The sequential activation of neurons has been observed during a range of behaviors and cognitive states and is central to many models of neural circuit function, but the synaptic connections enabling such dynamics are poorly understood. Song production in the zebra finch depends on a cortical region called HVC, which contains a major class of excitatory (HVC(RA)) neurons that fire action potential bursts in a fixed, sequential pattern during singing. These neurons not only project to downstream motor centers but also make numerous connections within HVC and could, therefore, form a sequence-generating synaptic chain. Evidence for this network architecture has, however, been either indirect or inconclusive. Here we employ light and transsynaptic electron microscopy to explore the synaptic connectivity of HVC(RA) neurons. We find that HVC(RA) cells receive the vast majority of their excitatory connections from distal sites on the axons of other HVC(RA) cells; proximal axonal sites, on the other hand, nearly always target inhibitory interneurons. Overall, this connectivity pattern provides evidence for a distributed excitatory synaptic chain supported by local inhibition, characteristic of coupled winner-take-all architectures.

Details

show
hide
Language(s):
 Dates: 2016-11
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: BibTex Citekey: KornfeldBNSODL2016
 Degree: -

Event

show
hide
Title: 46th Annual Meeting of the Society for Neuroscience (Neuroscience 2016)
Place of Event: San Diego, CA, USA
Start-/End Date: 2016-11-12 - 2016-11-16

Legal Case

show

Project information

show

Source 1

show
hide
Title: 46th Annual Meeting of the Society for Neuroscience (Neuroscience 2016)
Source Genre: Proceedings
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: - Sequence Number: 535.13 Start / End Page: - Identifier: -