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  Characterization of the macromolecular baseline with a metabolite-cycled double-inversion recovery sequence in the human brain at 9.4T

Giapitzakis, I., Kreis, R., & Henning, A. (2016). Characterization of the macromolecular baseline with a metabolite-cycled double-inversion recovery sequence in the human brain at 9.4T. In 24th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2016).

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Item Permalink: https://hdl.handle.net/21.11116/0000-0000-7CE0-8 Version Permalink: https://hdl.handle.net/21.11116/0000-0000-E982-6
Genre: Meeting Abstract

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Giapitzakis, IA1, 2, 3, Author           
Kreis, R, Author
Henning, A1, 2, 3, Author           
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1Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528692              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
3Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

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 Abstract: Macromolecular resonances (MM) overlap with metabolites resulting in inaccurate quantification of the metabolites due to baseline distortion. This effect becomes even more severe in case of short echo times (TE). The purpose of this study was the development of an adiabatic pulse for double inversion recovery and investigation of impact to include MM into quantification of 9.4T MRS data of human brain. This is the first study where MC-STEAM is combined with a double inversion technique. The results showed the advantages of UHF and MC as well as the necessity of the inclusion of MM baseline in the basis set.

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 Dates: 2016-05-09
 Publication Status: Issued
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 Identifiers: BibTex Citekey: GiapitzakisKH2016
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Title: 24th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2016)
Place of Event: Singapore
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Title: 24th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2016)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 0016 Start / End Page: - Identifier: -