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  Ultra low field magnetic resonance imaging for the investigation of hyperpolarized contrast agents

Rudolph, M., Misztal, T., Antkowiak, P., Meyer, H., Kleiner, R., Koelle, D., et al. (2016). Ultra low field magnetic resonance imaging for the investigation of hyperpolarized contrast agents. In 80. Jahrestagung der DPG und DPG-Frühjahrstagung.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0000-7D0C-8 Version Permalink: http://hdl.handle.net/21.11116/0000-0000-EC54-8
Genre: Meeting Abstract

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Rudolph, M, Author
Misztal, T, Author
Antkowiak, P1, Author              
Meyer, H, Author
Kleiner, R, Author
Koelle, D, Author
Scheffler, K1, 2, Author              
Buckenmaier, K1, 2, Author              
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: In NMR/MRI experiments at ultra low magnetic fields hyperpolarization techniques based on parahydrogen (pH2) could offer a simple way to circumvent the lack of the low equilibrium polarization of the sample. A chemical exchange reaction, taking place at B0 fields in the mT range, transfers polarized spins from pH2 via a transfer catalyst to the sample. This transfer reaction can enhance the sample polarization in B0 fields in the mT range by a factor of 105, offering sample polarizations comparable to polarization fields of 103-104 T. To investigate these newly developed techniques a SQUID based NMR/MRI system operating at a static magnetic field in the mT range is being developed. By using a SQUID for detecting the NMR Signal, the system can benefit from its very low intrinsic noise level. Additionally, SQUIDs are wide band detectors and can detect the signal of multiple kernels simultaneously. A design of an ultra low field MRI system and first results will be presented.

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 Dates: 2016-03
 Publication Status: Published in print
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 Identifiers: BibTex Citekey: RudolphMAMKKSB2016
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Title: 80. Jahrestagung der DPG und DPG-Frühjahrstagung
Place of Event: Regensburg, Germany
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Title: 80. Jahrestagung der DPG und DPG-Frühjahrstagung
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: TT 51.4 Start / End Page: - Identifier: -