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  The role of receptor subtype diversity in the CNS

Schofield, P. R., Shivers, B. D., & Seeburg, P. H. (1990). The role of receptor subtype diversity in the CNS. Trends in Neurosciences, 13(1), 8-11. doi:10.1016/0166-2236(90)90052-C.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0000-8435-F Version Permalink: https://hdl.handle.net/21.11116/0000-0000-8436-E
Genre: Journal Article

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TiNS_13_1990_8.pdf (Any fulltext), 535KB
 
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Schofield, Peter R., Author
Shivers, Brenda D., Author
Seeburg, Peter H.1, Author           
Affiliations:
1Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              

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 Abstract: The molecular characterization of neuroreceptors and voltage-gated ion channels has revealed that receptor subtype heterogeneity is a common feature of chemical and electrical signal reception. The use of distinct genes encoding receptor subtypes is a favoured mechanism for generation of this diversity. We propose that the significance of the multiplicity and diversity of signal reception proteins is to increase the information-handling capacity of neurons. This may contribute to neural plasticity.

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Language(s): eng - English
 Dates: 1990-01
 Publication Status: Issued
 Pages: 4
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/0166-2236(90)90052-C
URI: https://www.ncbi.nlm.nih.gov/pubmed/1688675
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Title: Trends in Neurosciences
  Other : Trends Neurosci.
Source Genre: Journal
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Publ. Info: Oxford : Elsevier Current Trends
Pages: - Volume / Issue: 13 (1) Sequence Number: - Start / End Page: 8 - 11 Identifier: ISSN: 0166-2236
CoNE: https://pure.mpg.de/cone/journals/resource/954927741850