English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  SQUID-based detection of ultra-low-field multinuclear NMR of substances hyperpolarized using signal amplification by reversible exchange

Buckenmaier, K., Rudolph, M., Black, C., Misztal, T., Bommerich, U., Fehling, P., et al. (2017). SQUID-based detection of ultra-low-field multinuclear NMR of substances hyperpolarized using signal amplification by reversible exchange. Scientific Reports, 7: 13431, pp. 1-9. doi:10.1038/s41598-017-13757-7.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0000-C2A6-9 Version Permalink: http://hdl.handle.net/21.11116/0000-0000-C2A7-8
Genre: Journal Article

Files

show Files

Locators

show
hide
Locator:
Link (Any fulltext)
Description:
-

Creators

show
hide
 Creators:
Buckenmaier, K1, 2, Author              
Rudolph, M1, 2, Author              
Black, C, Author
Misztal, T, Author
Bommerich, U, Author
Fehling, P, Author
Koelle, D, Author
Kleiner, R, Author
Mayer, HH, Author
Scheffler, K1, 2, Author              
Bernarding, J, Author
Plaumann, M, Author
Affiliations:
1Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
2Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

Content

show
hide
Free keywords: -
 Abstract: Ultra-low-field (ULF) nuclear magnetic resonance (NMR) is a promising spectroscopy method allowing for, e.g., the simultaneous detection of multiple nuclei. To overcome the low signal-to-noise ratio that usually hampers a wider application, we present here an alternative approach to ULF NMR, which makes use of the hyperpolarizing technique signal amplification by reversible exchange (SABRE). In contrast to standard parahydrogen hyperpolarization, SABRE can continuously hyperpolarize 1 H as well as other MR-active nuclei. For simultaneous measurements of 1 H and 19 F under SABRE conditions a superconducting quantum interference device (SQUID)-based NMR detection unit was adapted. We successfully hyperpolarized fluorinated pyridine derivatives with an up to 2000-fold signal enhancement in 19 F. The detected signals may be explained by two alternative reaction mechanisms. SABRE combined with simultaneous SQUID-based broadband multinuclear detection may enable the quantitative analysis of multinuclear processes.

Details

show
hide
Language(s):
 Dates: 2017-10
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1038/s41598-017-13757-7
BibTex Citekey: BuckenmaierRBMBFKKMSBP2017
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Scientific Reports
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 7 Sequence Number: 13431 Start / End Page: 1 - 9 Identifier: -