English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Depth-dependence of visual signals in the human superior colliculus at 9.4 T

Loureiro, J., Hagberg, G., Ethofer, T., Erb, M., Bause, J., Ehses, P., et al. (2017). Depth-dependence of visual signals in the human superior colliculus at 9.4 T. Human Brain Mapping, 38(1), 574-587. doi:10.1002/hbm.23404.

Item is

Files

show Files

Locators

show
hide
Locator:
Link (Any fulltext)
Description:
-
OA-Status:
Not specified

Creators

show
hide
 Creators:
Loureiro, JA1, Author           
Hagberg, G1, Author           
Ethofer, T, Author                 
Erb, M, Author           
Bause, J1, Author           
Ehses, P1, Author           
Scheffler, K1, Author           
Himmelbach, M, Author           
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

Content

show
hide
Free keywords: -
 Abstract: The superior colliculus (SC) is a layered structure located in the midbrain. We exploited the improved spatial resolution and BOLD signal strength available at 9.4 T to investigate the depth profile of visual BOLD responses in the human SC based on distortion-corrected EPI data with a 1 mm isotropic resolution. We used high resolution (350 µm in-plane) anatomical images to determine regions-of-interest of the SC and applied a semi-automated method to segment it into superficial, intermediate, and deep zones. A greater than linear increase in sensitivity of the functional signal at 9.4 T allowed us to detect a statistically significant depth pattern in a group analysis with a 20 min stimulation paradigm. Descriptive data showed consistent depth profiles also in single individuals. The highest signals were localized to the superficial layers of the right and left SC during contralateral stimulation, which was in good agreement with its functional architecture known from non-human primates. This study thus demonstrates the potential of 9.4 T MRI for functional neuroimaging even in deeply located, particularly challenging brain structures such as the SC.

Details

show
hide
Language(s):
 Dates: 2017-01
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1002/hbm.23404
BibTex Citekey: LoureiroHEEBESH2016
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Human Brain Mapping
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: New York : Wiley-Liss
Pages: - Volume / Issue: 38 (1) Sequence Number: - Start / End Page: 574 - 587 Identifier: ISSN: 1065-9471
CoNE: https://pure.mpg.de/cone/journals/resource/954925601686