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  SQUID-based ultralow field nuclear magnetic resonance spectroscopy using the para-H2 based hyperpolarization technique SABRE

Buckenmaier, K., Rudolph, M., Back, C., Engelmann, J., Rudin, J., Misztal, T., et al. (2017). SQUID-based ultralow field nuclear magnetic resonance spectroscopy using the para-H2 based hyperpolarization technique SABRE. Poster presented at 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0000-C4A1-C Version Permalink: http://hdl.handle.net/21.11116/0000-0000-F2C3-2
Genre: Poster

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 Creators:
Buckenmaier, K1, 2, Author              
Rudolph, M1, 2, Author              
Back, C, Author
Engelmann, J2, Author              
Rudin, J2, Author              
Misztal, T, Author
Bommerich, U, Author
Scheffler, K1, 2, Author              
Koelle, D, Author
Kleiner, R, Author
Mayer, H, Author
Bernarding, J, Author
Plaumann, M, Author
Affiliations:
1Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
2Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

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 Abstract: SABRE is a technique to achieve continuous hyperpolarization for MR measurements by the interaction of para-hydrogen and a substrate via steady ligand exchange on a catalyst. Thus, MR-active nuclei can be hyperpolarized more than only once. At field strengths of mT Faraday coils, commonly used in conventional or high field MRI, become insensitive and SQUIDs performing superior. Since SQUIDs are broadband detectors, the static magnetic field B0 can be changed easily or multiple nuclei can be measured simultaneously. Here, we successfully demonstrate the advantages of a SQUID based system by showing significant signal enhancement (1H, 19F) by hyperpolarization of 3-fluoropyridine.

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 Dates: 2017-04-27
 Publication Status: Published in print
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 Identifiers: BibTex Citekey: BuckenmaierRBERMBSKKMBP2017
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Title: 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017)
Place of Event: Honolulu, HI, USA
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Title: 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 3033 Start / End Page: - Identifier: -