hide
Free keywords:
-
Abstract:
SABRE is a technique to achieve continuous hyperpolarization for MR measurements by the interaction of para-hydrogen and a substrate via steady ligand exchange on a catalyst. Thus, MR-active nuclei can be hyperpolarized more than only once. At field strengths of mT Faraday coils, commonly used in conventional or high field MRI, become insensitive and SQUIDs performing superior. Since SQUIDs are broadband detectors, the static magnetic field B0 can be changed easily or multiple nuclei can be measured simultaneously. Here, we successfully demonstrate the advantages of a SQUID based system by showing significant signal enhancement (1H, 19F) by hyperpolarization of 3-fluoropyridine.
