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Abstract:
The neurovascular fingerprint of BOLD (blood oxygen level dependent) bSSFP (balanced steady-state free precession) is analyzed by Monte Carlo simulations for different vessel geometries and on a vectorized vessel data set of mouse parietal cortex. The results support that bSSFP yields vascular properties similar to those found with spin echo BOLD, a small intravascular signal contribution except for larger vessels, and a high selectivity to microvessels.