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要旨:
MRCDI aims at imaging an externally injected current flow in the human body, and might be useful for many biomedical applications. However, the method requires very sensitive measurement of the current-induced magnetic field component ?Bz,c parallel to main field. We systematically optimized MESE to determine its most efficient parameters. In one of the first human in-vivo applications of MRCDI, the optimized sequence was successfully used to image the ?Bz,c distribution in the brain caused by a two-electrode montage, as confirmed by finite-element calculations of ?Bz,c. Further improvements will be performed to increase its robustness to field drifts.
