English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  The Role of Internal Signals in Structuring V1 Population Activity

Denfield, G., Ecker, A., & Tolias, A. (2017). The Role of Internal Signals in Structuring V1 Population Activity. Poster presented at 27th Annual Rush and Helen Record Neuroscience Forum, Galveston, TX, USA.

Item is

Files

show Files

Locators

show
hide
Locator:
Link (Any fulltext)
Description:
-

Creators

show
hide
 Creators:
Denfield, GH, Author
Ecker, A1, 2, 3, Author              
Tolias, A2, 3, Author              
Affiliations:
1Research Group Computational Vision and Neuroscience, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497805              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
3Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              

Content

show
hide
Free keywords: -
 Abstract: Neuronal responses to repeated presentations of identical visual stimuli are variable. The source of this variability is unknown, but it is commonly treated as noise. We argue that this variability reflects, and is due to, computations internal to the brain. Relatively little research has examined the effect on neuronal responses of fluctuations in internal signals such as cortical state and attention, leaving a number of uncontrolled parameters that may contribute to neuronal variability. Attention increases neuronal response gain in a spatial and feature selective manner. We hypothesize that fluctuations in the strength and focus of attention are a major source of neuronal response variability and covariability. We first examine a simple model of a gain-modulating signal acting on a population of neurons and show that fluctuations in attention can increase individual and shared variability. To test our model’s predictions experimentally, we devised a cued-spatial attention, change-detection task to induce varying degrees of fluctuation in the subject’s attentional signal. We use multi-electrode recordings in primary visual cortex of macaques performing this task. We demonstrate that attention gain-modulates responses of V1 neurons in a manner consistent with results from higher-order areas. Our results also indicate neuronal covariability is elevated in conditions in which attention fluctuates. Overall, our results suggest that attentional fluctuations are an important contributor to neuronal variability and open the door to the use of statistical methods for inferring the state of these signals on behaviorally relevant timescales.

Details

show
hide
Language(s):
 Dates: 2017-02
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: BibTex Citekey: DenfieldET2017
 Degree: -

Event

show
hide
Title: 27th Annual Rush and Helen Record Neuroscience Forum
Place of Event: Galveston, TX, USA
Start-/End Date: -

Legal Case

show

Project information

show

Source 1

show
hide
Title: 27th Annual Rush and Helen Record Neuroscience Forum
Source Genre: Proceedings
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 31 - 31 Identifier: -