English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Over-discrete SENSE and B0 correction for accelerated 1H FID MRSI of the human brain at 9.4T

Nassirpour, S., Chang, P., & Henning, A. (2017). Over-discrete SENSE and B0 correction for accelerated 1H FID MRSI of the human brain at 9.4T. Magnetic Resonance Materials in Physics, Biology and Medicine, 30(Supplement 1), S112-S112.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0000-C540-9 Version Permalink: http://hdl.handle.net/21.11116/0000-0000-C541-8
Genre: Meeting Abstract

Files

show Files

Locators

show
hide
Locator:
Link (Any fulltext)
Description:
-

Creators

show
hide
 Creators:
Nassirpour, S1, 2, Author              
Chang, P1, 2, 3, Author              
Henning, A1, 2, 3, Author              
Affiliations:
1Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
2Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528692              
3Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

Content

show
hide
Free keywords: -
 Abstract: Purpose/Introduction: Over-discrete SENSE reconstruction with direct control of the shape of the spatial response function (SRF) [1] has been shown to reduce short- and far-reaching voxel bleeding. This makes it a suitable candidate for acceleration of non-lipid suppressed FIDMRSI, since lipid signals bleeding from the unsuppressed subcutaneous fat into the brain region become very problematic. Additionally, using the B0 map to correct for the frequency shifts on a sub-voxel level has been proven to provide SNR gain and line-shape improvement [2], which is especially beneficial for highly accelerated data. The aim of this work was to demonstrate the benefits of over-discrete SENSE reconstruction scheme along with the B0 correction on nonlipid suppressed ultra-short TR and TE 1H FID MRSI data at 9.4T. Subjects and Methods: High resolution (3.125mmx3.125mmx10 mm) single-slice ultra-short TR and TE non-lipid suppressed 1H FID MRSI [3–6] were acquired from the brains of healthy volunteers on a 9.4T Siemens whole-body human scanner with a TR of 300 ms. A high resolution scout anatomical image was used to extract the coil sensitivities using the ESPIRiT method [7], and high resolution B0 map was also acquired using a 2D GRE dual-echo sequence for B0 correction. The MRSI data was retrospectively undersampled by a factor of R = 2 9 2 and reconstructed with three schemes: (1) conventional SENSE, (2) over-discrete SENSE (OD-SENSE) with an over-discretization factor of 4, along with a Gaussian shape target matrix with the FWHM of the nominal voxel-size without and, (3) with B0 correction on a sub-voxel level (B0 OD-SENSE). Results: Figure 1 shows lipid contamination maps from the fully sampled along with the R = 4 times accelerated data reconstructed once with a conventional SENSE reconstruction scheme and once with the over-discrete scheme and direct control of the SRF The average SNR of the over-discrete reconstructed R = 2 9 2 SENSE data over the whole slice was 85.9 and 71.2, with and without the B0 correction, respectively. Discussion/Conclusion: In non-lipid suppressed MRSI, the lipid signals in the subcutaneous region are orders of magnitude larger than the metabolite signals. Therefore, any residual aliasing artifacts resulting from conventional SENSE reconstruction will overshadow the metabolites in the brain. The over-discrete reconstruction scheme greatly reduced this artifact as can be seen in Fig. 1. The over-discrete B0 correction resulted in 1.2 times gain in SNR which is in accordance with [2].

Details

show
hide
Language(s):
 Dates: 2017-10-19
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1007/s10334-017-0632-1
BibTex Citekey: NassirpourCH2017_5
 Degree: -

Event

show
hide
Title: 34th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB 2017)
Place of Event: Barcelona, Spain
Start-/End Date: -

Legal Case

show

Project information

show

Source 1

show
hide
Title: Magnetic Resonance Materials in Physics, Biology and Medicine
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 30 (Supplement 1) Sequence Number: - Start / End Page: S112 - S112 Identifier: -