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  In-vivo and ex-vivo R2* and Quantitative Susceptibility Mapping in Alzheimer’s Disease at Ultra-High Magnetic Field compared to Histology

Tuzzi, E., Hagberg, G., Balla, D., Loureiro, J., Neumann, M., Laske, C., et al. (2017). In-vivo and ex-vivo R2* and Quantitative Susceptibility Mapping in Alzheimer’s Disease at Ultra-High Magnetic Field compared to Histology. In 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017) (pp. 677-678).

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Item Permalink: http://hdl.handle.net/21.11116/0000-0000-C5A2-A Version Permalink: http://hdl.handle.net/21.11116/0000-0000-F9F8-0
Genre: Meeting Abstract

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 Creators:
Tuzzi, E1, 2, Author              
Hagberg, G1, 2, Author              
Balla, D1, 2, 3, Author              
Loureiro, J2, Author              
Neumann, M, Author
Laske, C, Author
Pohmann, R1, 2, 4, Author              
Valverde, M2, 3, Author              
Affiliations:
1Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
2Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
3Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
4Dept. Empirical Inference, Max Planck Institute for Intelligent Systems, Max Planck Society, ou_1497647              

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 Abstract: Amyloid-β plaques are classical hallmarks of the post-mortem Alzheimer’s Disease (AD) brain. Ultra-High-Field (UHF) MRI provides a compelling means to investigate pathological processes at an unprecedented level of detail. ß-amyloid plaques can be detected in T2* weighted images at UHF, ex-vivo, due to the local iron content and to the plaque geometry per sè. With this study we aim to explore the source of the observed MR signal changes in AD at UHF using quantitative MRI methods in-vivo and ex-vivo.

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 Dates: 2017-04-27
 Publication Status: Published in print
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 Identifiers: BibTex Citekey: TuzziHBLNLPV2017
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Title: 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017)
Place of Event: Honolulu, HI, USA
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Title: 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 1170 Start / End Page: 677 - 678 Identifier: -