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  Mapping the task-related and resting-state vascular dynamic network connectivity in rats and humans

He, Y., Pohmann, R., Scheffler, K., Kleinfeld, D., Rosen, B., & Yu, X. (2017). Mapping the task-related and resting-state vascular dynamic network connectivity in rats and humans. In 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017) (pp. 304-305).

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He, Y1, 2, 3, Author           
Pohmann, R2, 3, Author           
Scheffler, K2, 3, Author           
Kleinfeld, D, Author
Rosen, B, Author
Yu, X2, 3, Author           
Affiliations:
1Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528695              
2Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
3Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: We have previously shown that hemodynamic signals can be directly detected from individual arterioles and venules penetrating the cortex. Here, the temporal correlation patterns of the vessel-specific hemodynamic signal are characterized in both rodent and human brains. At the resting state, the blood-oxygen-level-dependent (BOLD) signal from venules and the cerebral blood volume (CBV) signal from arterioles show large-scale vessel-specific correlation patterns in rats under anesthesia. Similarly, in awake human subjects, the BOLD hemodynamic signal correlated at the sulcus veins (3T), as well as at a few intra-cortical veins detected at 9.4T, showing vessel-specific activity and connectivity patterns with slow-frequency oscillation up to 0.1Hz.

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 Dates: 2017-04-25
 Publication Status: Issued
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 Identifiers: BibTex Citekey: HePSKRY2017
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Title: 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017)
Place of Event: Honolulu, HI, USA
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Title: 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 0459 Start / End Page: 304 - 305 Identifier: -