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Abstract:
We evaluated the ability of diffusion MRI-based tractography to identify macaque vertical occipital fasciculus (VOF), an important but little-studied white-matter tract connecting dorsal and ventral visual cortex. We analyzed four macaque diffusion MRI datasets with different resolution. The high-resolution post-mortem dataset reliably detects the macaque VOF, in a consistent manner with previous invasive anatomical studies. Lower resolution in vivo data showed qualitatively consistent results, but the estimated tract endpoints are restricted to sulcus. Taken together, our results demonstrate that the need for high-resolution diffusion MRI to identify certain critical white matter tracts.
