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  Molecular biology of the GABAA receptor: the receptor/channel superfamily

Barnard, E. A., Darlison, M. G., & Seeburg, P. H. (1987). Molecular biology of the GABAA receptor: the receptor/channel superfamily. Trends in Neurosciences, 10(12), 502-509. doi:10.1016/0166-2236(87)90130-5.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0000-C893-8 Version Permalink: https://hdl.handle.net/21.11116/0000-0000-C894-7
Genre: Journal Article

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TiNS_10_1987_502.pdf (Any fulltext), 2MB
 
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Barnard, Eric A., Author
Darlison, Mark G., Author
Seeburg, Peter H.1, Author           
Affiliations:
1Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              

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 Abstract: Complementary DNAs encoding the two subunit types of the brain GABAA receptor have been cloned, revealing its full protein primary structure1. In another laboratory, the same point has now been reached for one of the subunits of the spinal cord glycine receptor2. It is illuminating to compare these sequences and those of the nicotinic acetylcholine receptor. All of these receptors, in which an ion channel is directly gated by the binding of the transmitter, are deducéd to be members of a receptor superfamily and exhibit some striking common features in their architecture.

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Language(s): eng - English
 Dates: 2003-03-051987-12
 Publication Status: Issued
 Pages: 8
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/0166-2236(87)90130-5
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Title: Trends in Neurosciences
  Other : Trends Neurosci.
Source Genre: Journal
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Publ. Info: Oxford : Elsevier Current Trends
Pages: - Volume / Issue: 10 (12) Sequence Number: - Start / End Page: 502 - 509 Identifier: ISSN: 0166-2236
CoNE: https://pure.mpg.de/cone/journals/resource/954927741850