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キーワード:
animation; homogeneous catalysis; P ligand; palladium; Suzuki cross-coupling
要旨:
We describe herein an air stable phosphorus ligand for both Suzuki-Miyaura and Buchwald-Hartwig palladium-catalyzed cross coupling reactions. The versatility of the Pd(dba)2-di-tert-butyl N,N-diethylphosphoramidite catalytic system is demonstrated for a variety of aryl and heteroaryl halides. This ligand is "bench stable" which allows easy catalyst preparation. Moreover, even at low catalyst loadings (0.5 %), excellent yields are usually achieved.
