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  Pseudomonas aeruginosa secretes and correctly processes human growth hormone

Gray, G. L., McKeown, K. A., Jones, A. J. S., Seeburg, P. H., & Heyneker, H. L. (1984). Pseudomonas aeruginosa secretes and correctly processes human growth hormone. Nature Biotechnology, 2, 161-165. doi:10.1038/nbt0284-161.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0000-D579-8 Version Permalink: https://hdl.handle.net/21.11116/0000-0000-D57A-7
Genre: Journal Article

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NatBiotechnol_2_1984_161.pdf (Any fulltext), 831KB
 
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https://www.nature.com/articles/nbt0284-161.pdf (Any fulltext)
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https://doi.org/10.1038/nbt0284-161 (Any fulltext)
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 Creators:
Gray, Gregory L., Author
McKeown, Kathleen A., Author
Jones, Andrew J. S., Author
Seeburg, Peter H.1, Author           
Heyneker, Herbert L., Author
Affiliations:
1Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              

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 Abstract: Pseudomonas aeruginosa transformed with a plasmid containing a gene encoding the mature form of human growth hormone (hGH) preceded by an ATG codon to initiate translation expresses methionyl-hGH its cytoplasm. hGH produced in P. aeruginosa cells transformed with a plasmid containing a gene for the natural hGH precursor is transported across the inner membrane and has the NH2-terminal amino acid sequence of authentic mature hGH.

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Language(s): eng - English
 Dates: 1984-02-011984-02-01
 Publication Status: Issued
 Pages: 5
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1038/nbt0284-161
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Title: Nature Biotechnology
Source Genre: Journal
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Publ. Info: New York : Gale Group Inc.
Pages: - Volume / Issue: 2 Sequence Number: - Start / End Page: 161 - 165 Identifier: ISSN: 1087-0156
CoNE: https://pure.mpg.de/cone/journals/resource/954926980065