English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
  Differentiation-dependent changes of nicotinic synapse-associated proteins

Witzemann, V., Schmid, D., & Boustead, C. (1983). Differentiation-dependent changes of nicotinic synapse-associated proteins. European Journal of Biochemistry, 131(2), 235-245. doi:10.1111/j.1432-1033.1983.tb07255.x.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0000-E5AC-C Version Permalink: http://hdl.handle.net/21.11116/0000-0000-E5AD-B
Genre: Journal Article

Files

show Files
hide Files
:
EurJBiochem_131_1983_235.pdf (Any fulltext), 3MB
 
File Permalink:
-
Name:
EurJBiochem_131_1983_235.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute for Medical Research, MHMF; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Witzemann, Veit1, 2, 3, 4, Author              
Schmid, D., Author
Boustead, Catherine, Author
Affiliations:
1Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              
2Working Group Witzemann / Koenen, Max Planck Institute for Medical Research, Max Planck Society, ou_1497748              
3Molecular anatomy of the neuromuscular junction, Max Planck Institute for Medical Research, Max Planck Society, ou_1497727              
4Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497701              

Content

show
hide
Free keywords: -
 Abstract: Developmentally regulated changes were followed by analyzing the protein composition in vivo of the electric organ of Torpedo marmorata. A 45 000-Mr component, most likely a form of actin, is found to decrease during synaptogenesis, whereas a 43 000-Mr component increases significantly at later embryonic stages, to become the most abundant protein of electric organ. The 43 000-Mr polypeptides are heterogeneous in their solubilization properties and isoelectric points. Translation in vitro of mRNA isolated from embryonic electric organ shows that the appearance of these proteins during development is regulated by the amount of translatable mRNA available. The close correlation between the translatable amounts of mRNA in vitro and the protein synthesis observed in vivo during synaptogenesis suggests that the functional maturation of the electric organ is linked to the appearance of 43 000-Mr polypeptides.

Details

show
hide
Language(s): eng - English
 Dates: 1982-10-221982-11-301983-03
 Publication Status: Published in print
 Pages: 11
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: European Journal of Biochemistry
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Berlin : Published by Springer-Verlag on behalf of the Federation of European Biochemical Societies
Pages: - Volume / Issue: 131 (2) Sequence Number: - Start / End Page: 235 - 245 Identifier: ISSN: 0014-2956
CoNE: https://pure.mpg.de/cone/journals/resource/111097776606040