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  Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA

Comb, M., Seeburg, P. H., Adelman, J. P., Eiden, L., & Herbert, E. (1982). Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA. Nature, 295(5851), 663-666. doi:10.1038/295663a0.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0000-F08D-2 Version Permalink: https://hdl.handle.net/21.11116/0000-0000-F08E-1
Genre: Journal Article

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Nature_295_1982_663.pdf (Any fulltext), 512KB
 
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 Creators:
Comb, Michael, Author
Seeburg, Peter H.1, Author           
Adelman, John P., Author
Eiden, Lee, Author
Herbert, Edward, Author
Affiliations:
1Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              

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 Abstract: The nucleotide sequence of a complete cDNA copy of enkephalin precursor mRNA from human phaeochromocytoma is reported. The corresponding amino acid sequence shows that the precursor is 267 amino acids long and contains six interspersed Met-enkephalin sequences and one Leu-enkephalin sequence. Five of the seven enkephalins are flanked on both sides by pairs of basic amino acid residues. The precursors does not contain the sequences of the opioid peptides, dynorphin, alpha-neo-endorphin or beta-endorphin.

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Language(s): eng - English
 Dates: 1981-12-281982-01-151982-02-25
 Publication Status: Issued
 Pages: 4
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1038/295663a0
URI: https://www.ncbi.nlm.nih.gov/pubmed/7057924
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Title: Nature
  Abbreviation : Nature
Source Genre: Journal
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Publ. Info: London : Nature Publishing Group
Pages: - Volume / Issue: 295 (5851) Sequence Number: - Start / End Page: 663 - 666 Identifier: ISSN: 0028-0836
CoNE: https://pure.mpg.de/cone/journals/resource/954925427238