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  Scaling and regeneration of self-organized patterns.

Werner, S., Stückemann, T., Amigo, M. B., Rink, J., Jülicher, F., & Friedrich, B. (2015). Scaling and regeneration of self-organized patterns. Physical Review Letters, 114(13): 138101.

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 Creators:
Werner, Steffen, Author
Stückemann, Tom1, Author           
Amigo, Manuel Beirán, Author
Rink, Jochen1, Author           
Jülicher, Frank, Author
Friedrich, Benjamin2, Author
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1Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society, ou_2340692              
2Max Planck Society, ou_persistent13              

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 Abstract: Biological patterns generated during development and regeneration often scale with organism size. Some organisms, e.g., flatworms, can regenerate a rescaled body plan from tissue fragments of varying sizes. Inspired by these examples, we introduce a generalization of Turing patterns that is self-organized and self-scaling. A feedback loop involving diffusing expander molecules regulates the reaction rates of a Turing system, thereby adjusting pattern length scales proportional to system size. Our model captures essential features of body plan regeneration in flatworms as observed in experiments.

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 Dates: 2015
 Publication Status: Issued
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 Identifiers: eDoc: 718065
Other: 6186
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Title: Physical Review Letters
Source Genre: Journal
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Pages: - Volume / Issue: 114 (13) Sequence Number: 138101 Start / End Page: - Identifier: -