4Alpha-bromo-5alpha-cholestan-3beta-ol and nor-5alpha-cholestan-3beta-ol 
derivatives-stereoselective synthesis and hormonal activity in Caenorhabditis 
elegans

Martin, Rene; Saini, Ratni; Bauer, Ingmar; Gruner, Margit; Kataeva, Olga; Zagoriy, Vyacheslav; Entchev, Eugeni V; Kurzchalia, Teymuras V; Knolker, Hans-Joachim

Local TagsRelease HistoryDetailsSummary

4Alpha-bromo-5alpha-cholestan-3beta-ol and nor-5alpha-cholestan-3beta-ol derivatives-stereoselective synthesis and hormonal activity in Caenorhabditis elegans

Martin, R., Saini, R., Bauer, I., Gruner, M., Kataeva, O., Zagoriy, V., et al. (2009). 4Alpha-bromo-5alpha-cholestan-3beta-ol and nor-5alpha-cholestan-3beta-ol derivatives-stereoselective synthesis and hormonal activity in Caenorhabditis elegans. Organic & Biomolecular Chemistry, 7(11), 2303-2309.

Item is Released

show all hide all

Basic

show hide

Item Permalink: https://hdl.handle.net/21.11116/0000-0001-0CAE-F Version Permalink: https://hdl.handle.net/21.11116/0000-0001-0CAF-E

Genre: Journal Article

Files

show Files

Locators

show

Creators

show

hide

Creators:
Martin, Rene, Author
Saini, Ratni, Author
Bauer, Ingmar, Author
Gruner, Margit, Author
Kataeva, Olga, Author
Zagoriy, Vyacheslav¹, Author
Entchev, Eugeni V¹, Author
Kurzchalia, Teymuras V¹, Author
Knolker, Hans-Joachim, Author

Affiliations:
1Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society, ou_2340692

Content

show

hide

Free keywords: -

Abstract: We describe the stereoselective synthesis of 4alpha-bromo-5alpha-cholestan-3beta-ol, 21-nor-5alpha-cholestan-3beta-ol, 27-nor-5alpha-cholestan-3beta-ol and 21,27-bisnor-5alpha-cholestan-3beta-ol. In order to clarify the in vivo metabolism of cholesterol, these compounds have been used for feeding experiments in Caenorhabditis elegans. Our preliminary results provide important insights into the metabolism of cholesterol in worms.

Details

show

hide

Language(s):

Dates: Date issued: 2009

Publication Status: Issued

Pages: -

Publishing info: -

Table of Contents: -

Rev. Type: -

Identifiers: eDoc: 463211
Other: 1334

Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show

hide

Title: Organic & Biomolecular Chemistry

Source Genre: Journal

Creator(s):

Affiliations:

Publ. Info: -

Pages: - Volume / Issue: 7 (11) Sequence Number: - Start / End Page: 2303 - 2309 Identifier: -