English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Multiple roles for lipids in the Hedgehog signalling pathway

Eaton, S. (2008). Multiple roles for lipids in the Hedgehog signalling pathway. Nature Reviews. Molecular Cell Biology, 9(6), 437-445.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Eaton, Suzanne1, Author           
Affiliations:
1Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society, ou_2340692              

Content

show
hide
Free keywords: -
 Abstract: The identification of endogenous sterol derivatives that modulate the Hedgehog (Hh) signalling pathway has begun to suggest testable hypotheses for the cellular biological functions of Patched, and for the lipoprotein association of Hh. Progress in the field of intracellular sterol trafficking has emphasized how tightly the distribution of intracellular sterol is controlled, and suggests that the synthesis of sterol derivatives can be influenced by specific sterol-delivery pathways. The combination of this field with Hh studies will rapidly give us a more sophisticated understanding of both the Hh signal-transduction pathway and the cell biology of sterol metabolism.

Details

show
hide
Language(s):
 Dates: 2008
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: eDoc: 414403
Other: 1154
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Nature Reviews. Molecular Cell Biology
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 9 (6) Sequence Number: - Start / End Page: 437 - 445 Identifier: -