hide
Free keywords:
-
Abstract:
Previously, the relevance of lipoproteins and their receptors has
mainly been discussed in terms of cholesterol clearance in the
adult organism. Now, findings from nematodes to fruit flies to
mammals all point towards novel and unexpected roles for
lipoprotein metabolism in the control of key regulatory
pathways in the developing embryo, including signaling
through steroid hormones and throughout the hedgehog and
Wnt signaling pathways. Here, we discuss the emerging view of
how lipoproteins and their receptors regulate embryogenesis.
