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  Possible role of parotid adrenergic beta-receptors in sialadenosis

Arglebe, C., Chilla, R., & Witzemann, V. (1980). Possible role of parotid adrenergic beta-receptors in sialadenosis. In Advances in Physiological Sciences (pp. 335-340). doi:10.1016/B978-0-08-027349-5.50053-7.

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 Creators:
Arglebe, Christian, Author
Chilla, R., Author
Witzemann, Veit1, 2, 3, 4, Author           
Affiliations:
1Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              
2Working Group Witzemann / Koenen, Max Planck Institute for Medical Research, Max Planck Society, ou_1497748              
3Molecular anatomy of the neuromuscular junction, Max Planck Institute for Medical Research, Max Planck Society, ou_1497727              
4Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497701              

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 Abstract: This chapter discusses the behavior of beta-adrenoceptors in various nontumorous diseases of the cephalic salivary glands, such as sialadenosis, chronic-recurrent sialadenitis, and myoepithelial sialadenitis. Sialadenosis is a noninflammatory disease mainly of the parotid gland. It is clinically characterized by a diffuse bilateral swelling of the parotid gland, giving the face a hamster-like appearance. In one of the experiments described in the chapter, three human sialadenoses were tested. There was a distinct increase in beta-adrenoceptor concentration, suggesting involvement in sialadenosis of acinar cell denervation. A comparable increase in beta-adrenoceptors was also found in five cases of sialadenitis and was again accompanied by low amylase levels. Destruction of vegetative nerve terminals by inflammation could have caused denervation of acinar cells. Contamination of membrane fragments from acinar cells with membranes of inflammation cells could have simulated the effect of acinar cell denervation.

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Language(s): eng - English
 Dates: 198019801980-10-211980
 Publication Status: Issued
 Pages: 6
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

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Title: Advances in Physiological Sciences
  Alternative Title : satellite symposium of the 28th international congress of physiological sciences held at SzeÌkesfeheÌrvaÌr, Hungary, 1980
Source Genre: Book
 Creator(s):
Zelles, T., Author
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-
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Pages: - Volume / Issue: 28 Sequence Number: - Start / End Page: 335 - 340 Identifier: -