English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Deficient approaches to human neuroimaging

Stelzer, J., Lohmann, G., Mueller, K., Buschmann, T., & Turner, R. (2014). Deficient approaches to human neuroimaging. Frontiers in Human Neuroscience, 8: 462, pp. 1-16. doi:10.3389/fnhum.2014.00462.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0001-29BF-B Version Permalink: http://hdl.handle.net/21.11116/0000-0001-8CDE-8
Genre: Journal Article

Files

show Files

Locators

show
hide
Description:
-

Creators

show
hide
 Creators:
Stelzer, Johannes, Author              
Lohmann, Gabriele1, 2, Author              
Mueller, Karsten, Author              
Buschmann, Tilo, Author              
Turner, Robert, Author              
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

Content

show
hide
Free keywords: fMRI; Cognitive neuroscience; Brain mapping; Functional localization; Critical neuroscience
 Abstract: Functional magnetic resonance imaging (fMRI) is the workhorse of imaging-based human cognitive neuroscience. The use of fMRI is ever-increasing; within the last 4 years more fMRI studies have been published than in the previous 17 years. This large body of research has mainly focused on the functional localization of condition- or stimulus-dependent changes in the blood-oxygenation-level dependent signal. In recent years, however, many aspects of the commonly practiced analysis frameworks and methodologies have been critically reassessed. Here we summarize these critiques, providing an overview of the major conceptual and practical deficiencies in widely used brain-mapping approaches, and exemplify some of these issues by the use of imaging data and simulations. In particular, we discuss the inherent pitfalls and shortcomings of methodologies for statistical parametric mapping. Our critique emphasizes recent reports of excessively high numbers of both false positive and false negative findings in fMRI brain mapping. We outline our view regarding the broader scientific implications of these methodological considerations and briefly discuss possible solutions.

Details

show
hide
Language(s): eng - English
 Dates: 2014-07
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.3389/fnhum.2014.00462
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Frontiers in Human Neuroscience
  Abbreviation : Front Hum Neurosci
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 8 Sequence Number: 462 Start / End Page: 1 - 16 Identifier: ISSN: 1662-5161
CoNE: https://pure.mpg.de/cone/journals/resource/1662-5161