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  Regulation of growth hormone messenger RNA

Martial, J. A., Seeburg, P. H., Matulich, D. T., Goodman, H. M., & Baxter, J. D. (1979). Regulation of growth hormone messenger RNA. In J. D. Baxter, & G. G. Rousseau (Eds.), Monographs on endocrinology (Chapter 15, pp. 279-289). Heidelberg / Berlin / New York: Springer.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0001-29EB-9 Version Permalink: https://hdl.handle.net/21.11116/0000-0001-29EC-8
Genre: Book Chapter

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Baxter_1979_MonographsEndocrinology_279.pdf (Any fulltext), 795KB
 
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 Creators:
Martial, Joseph A., Author
Seeburg, Peter H.1, Author           
Matulich, D. T., Author
Goodman, Howard M., Author
Baxter, John D., Author
Affiliations:
1Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              

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 Abstract: In cultured rat pituitary cells, glucocorticoids regulate growth hormone production by modulating the number of growth hormone messenger RNA molecules. The effect is quite specific, since only a few other mRNAs are affected by the hormones. This response is demonstrated by assays involving cell-free mRNA translation and cDNA-RNA hybridization. Furthermore, the inducibility by the glucocorticoids is regulated by at least one other class of hormones, thyroid hormone. Thus, this system serves as a model for studying not only the glucocorticoid regulation of specific mRNA, but also the control of this regulation by other factors in the target tissue.

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Language(s): eng - English
 Dates: 1979
 Publication Status: Issued
 Pages: 11
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
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Title: Monographs on endocrinology
  Alternative Title : Glucocorticoid Hormone Action
Source Genre: Book
 Creator(s):
Baxter, John D., Editor
Rousseau, Guy G., Editor
Affiliations:
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Publ. Info: Heidelberg / Berlin / New York : Springer, Chapter 15
Pages: 638 Volume / Issue: - Sequence Number: - Start / End Page: 279 - 289 Identifier: ISSN: 0077-1015