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Abstract:
Asymmetric adiabatic pulses have been used for metabolite cycled 1H-MRS at 3 Tesla and 7 Tesla enabling better spectral resolution and post-processing of the measured data without scan time prolongation. In this abstract, the frequency excitation profile of the adiabatic pulses was extensively studied with regards to time duration, the B1+ field and the frequency sweep range. Optimum values for the characteristics of the inversion pulses were found for implementation in a STEAM sequence at 9.4T. Both phantom and in vivo measurements on a healthy volunteer verified the simulations and showed that metabolite cycled 1H-MRS is feasible at 9.4T.