English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Reverse engineering sensory perception and decision making: bridging physiology, anatomy and behavior

Oberlaender, M. (2014). Reverse engineering sensory perception and decision making: bridging physiology, anatomy and behavior. Talk presented at Erasmus University 2014 Seminar Series. Rotterdam, The Netherlands.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0001-33D6-4 Version Permalink: http://hdl.handle.net/21.11116/0000-0001-36C2-7
Genre: Talk

Files

show Files

Locators

show
hide
Description:
-

Creators

show
hide
 Creators:
Oberlaender, Marcel1, 2, Author              
Affiliations:
1Former Research Group Computational Neuroanatomy, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528698              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

Content

show
hide
Free keywords: -
 Abstract: Understanding how the brain is able to transform sensory input into decisions is one of the major challenges of systems neuroscience. While recording/imaging during sensory-motor tasks identified neural substrates of sensation and action in various cortical areas, the crucial questions of 1) how these correlates are implemented within the underlying neural networks and 2) how their output triggers decisions, will only be answered when the individual functional measurements are integrated into a coherent model of all task-related circuits. The goal of our research is to use the rodent vibrissal system for building such a model in the context of how a tactile-mediated percept is encoded by the interplay between biophysical, cellular and network mechanisms. Specifically, rodents decide to cross a gap when detecting its far side with a single facial whisker. This suggests that whisker contact with the platform, if synchronized with an internal motor signal, triggers the decision. To test this hypothesis, we will determine all sensory/motor-related local and long-range whisker pathways, measure whisker-evoked responses of these populations and use the data to constrain network simulations of active whisker touch. Using a multidisciplinary approach, combining in vivo electrophysiology, virus injections, custom imaging/reconstruction tools and Monte Carlo simulations, our reverse engineering strategy will provide unmatched mechanistic insight to perceptual decision making and will function as a show case - generalizable across sensory modalities and species - of how to derive computations that underlie behavior.

Details

show
hide
Language(s):
 Dates: 2014-06-02
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: BibTex Citekey: Oberlaender2014_6
 Degree: -

Event

show
hide
Title: Erasmus University 2014 Seminar Series
Place of Event: Rotterdam, The Netherlands
Start-/End Date: -
Invited: Yes

Legal Case

show

Project information

show

Source

show