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  Deciphering the genome and secondary metabolome of the plant pathogen Fusarium culmorum

Schmidt, R., Durling, M. B., de Jager, V., Menezes, R. C., Nordkvist, E., Svatoš, A., et al. (2018). Deciphering the genome and secondary metabolome of the plant pathogen Fusarium culmorum. FEMS Microbiology Ecology, 94(6), 1-12. doi:10.1093/femsec/fiy078.

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 Creators:
Schmidt, Ruth, Author
Durling, Mikael B, Author
de Jager, Victor, Author
Menezes, Riya Christina1, Author           
Nordkvist, Erik, Author
Svatoš, Aleš1, Author           
Dubey, Mukesh, Author
Lauterbach, Lukas, Author
Dickschat, Jeroen S, Author
Karlsson, Magnus, Author
Garbeva, Paolina, Author
Affiliations:
1Research Group Mass Spectrometry, MPI for Chemical Ecology, Max Planck Society, ou_421899              

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 Abstract: Fusarium culmorum is one of the most important fungal plant pathogens that causes diseases on a wide diversity of cereal and non-cereal crops. We report herein for the first time the genome sequence of F. culmorum strain PV and its associated secondary metabolome that plays a role in the interaction with other microorganisms and contributes to its pathogenicity on plants. The genome revealed the presence of two terpene synthases, trichodiene and longiborneol synthase, which generate an array of volatile terpenes. Furthermore, we identified two gene clusters, DON and ZEN, which encode for the production of mycotoxins. Linking the production of mycotoxins with in vitro bioassays, we found high virulence of F. culmorum PV on maize, barley and wheat. By using UPLC/MS, we confirmed several compounds important for the behaviour and lifestyle of F. culmorum. This research sets the basis for future studies in microbe-plant interactions.

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 Dates: 2018-04-202018-04-302018-06
 Publication Status: Issued
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 Identifiers: Other: MS191
DOI: 10.1093/femsec/fiy078
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Title: FEMS Microbiology Ecology
Source Genre: Journal
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Publ. Info: Amsterdam : No longer published by Elsevier
Pages: - Volume / Issue: 94 (6) Sequence Number: - Start / End Page: 1 - 12 Identifier: ISSN: 0168-6496
CoNE: https://pure.mpg.de/cone/journals/resource/954925526820_1