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  MaxSynBio - Avenues towards creating cells from the bottom up

Schwille, P., Spatz, J., Landfester, K., Bodenschatz, E., Herminghaus, S., Sourjik, V., et al. (2018). MaxSynBio - Avenues towards creating cells from the bottom up. Angewandte Chemie International Edition, 57(41), 13382-13392. doi:10.1002/anie.201802288.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0001-64C1-4 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-A89C-0
Genre: Journal Article

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 Creators:
Schwille, P.1, Author
Spatz, J.2, Author
Landfester, K.3, Author
Bodenschatz, Eberhard4, Author              
Herminghaus, Stephan5, Author              
Sourjik, V.6, Author
Erb, T.6, Author
Bastiaens, P.7, Author
Lipowsky, R.8, Author
Hyman, A.9, Author
Dabrock, P.10, Author
Baret, J. P.11, Author
Vidaković-Koch, Tanja12, Author              
Bieling, P.7, Author
Dimova, R.8, Author
Mutschler, H.1, Author
Robinson, T.8, Author
Tang, D.9, Author
Wegner, S.3, Author
Sundmacher, Kai12, Author              
Affiliations:
1Max Planck Institute of Biochemistry, Dptm. of Cellular and Molecular Biophysics, , Martinsried, ou_persistent22              
2Max Planck Institute for Medical Research, Max Planck Society, Jahnstrasse 29, 69120 Heidelberg, DE, ou_1125545              
3Max Planck Institute for Polymer Research, Mainz, ou_persistent22              
4Laboratory for Fluid Dynamics, Pattern Formation and Biocomplexity, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society, ou_2063287              
5Grenzflächen, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863287              
6Max Planck Institute for Terrestrial Microbiology, Marburg, ou_persistent22              
7Max Planck Institute for Molecular Physiology, Dortmund, ou_persistent22              
8Max Planck Institute of Colloids and Interfaces, Potsdam, ou_persistent22              
9Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, ou_persistent22              
10Friedrich-Alexander-Universität Nürnberg-Erlangen, ou_persistent22              
11Universität Bordeaux, ou_persistent22              
12Process Systems Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society, ou_1738151              

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Free keywords: Synthetic Biology, Protocells, Microfluidics, Cell-free, Bottom-up
 Abstract: A large Max Planck‐based German research consortium ('MaxSynBio') was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom‐up approach to Synthetic Biology. MaxSynBio focuses on the detailed analysis and understanding of essential processes of life, via their modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non‐living components. The fundamental insights gained from the activities in MaxSynBio can eventually be utilized for establishing a new generation of biotechnological processes, which would be based on synthetic cell constructs that replace natural cells currently used in conventional biotechnology.

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Language(s): eng - English
 Dates: 2018
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1002/anie.201802288
 Degree: -

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Title: Angewandte Chemie International Edition
  Abbreviation : Angew. Chem.
Source Genre: Journal
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Affiliations:
Publ. Info: Weinheim : Wiley-VCH
Pages: - Volume / Issue: 57 (41) Sequence Number: - Start / End Page: 13382 - 13392 Identifier: -