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  Cerebral blood volume changes in negative BOLD regions during visual stimulation in humans at 7T

Huber, L., Goense, J., Ivanov, D., Krieger, S., Turner, R., & Möller, H. (2013). Cerebral blood volume changes in negative BOLD regions during visual stimulation in humans at 7T. In 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013).

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 Creators:
Huber, L, Author
Goense, JBM1, 2, Author           
Ivanov, D, Author
Krieger, S, Author
Turner, R, Author
Möller, HE, Author
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: Based on recent studies in monkeys (Goense, J, et al., Neuron, in press), the changes in cerebral blood volume (CBV) were investigated in human brain regions that show negative BOLD responses during a visual task. Therefore a CBV-sensitive VASO method was implemented that can account for BOLD and inflow contaminations at 7T. In regions with negative BOLD responses, significant CBV decreases can be seen. This CBV decrease is dominated by voxels that include the cortical surface at the transition region between grey matter and cerebrospinal fluid, while many voxels in deeper layers show a CBV increase.

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 Dates: 2013-04-202013-04
 Publication Status: Issued
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Title: 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013)
Place of Event: Salt Lake City, UT, USA
Start-/End Date: 2013-04-20 - 2013-04-26

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Title: 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 0847 Start / End Page: - Identifier: -