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  Extended metabolite profile of the human spinal cord

Hock, A., Wilm, B., MacMillan, E., Kreis, R., Kollias, S., Boesiger, P., et al. (2013). Extended metabolite profile of the human spinal cord. Poster presented at 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT, USA.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0001-5582-C Version Permalink: https://hdl.handle.net/21.11116/0000-0001-5583-B
Genre: Poster

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https://www.ismrm.org/13/tp15.htm (Abstract)
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 Creators:
Hock, A, Author
Wilm, BJ, Author
MacMillan, EL, Author
Kreis, R, Author
Kollias, SS, Author
Boesiger, P, Author
Henning, A1, 2, Author           
Affiliations:
1Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528692              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: Clinical magnetic resonance spectroscopy is rarely applied in the spinal cord due to technical challenges leading to a low spectral quality and thus to a limited number of reliable detectable metabolites. In order to extend the metabolite profile an increase of the spectral quality is necessary, which could be achieved by both: averaging a high number of FIDs and by using a dedicated neck coil. Besides N-acetyl aspartate, creatine, choline and myo-inositol a reliable detection of scyllo-inositol and glutamine/glutamate was possible. Increased myo-inositol/creatine and scyllo-inositol/creatine ratios compared to brain estimates can be observed in the spinal cord.

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 Dates: 2013-04
 Publication Status: Issued
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Title: 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013)
Place of Event: Salt Lake City, UT, USA
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Title: 21st Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 1113 Start / End Page: - Identifier: -