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Abstract:
The development and implementation of the CMRO2 imaging approach based on high-field 17O magnetic resonance spectroscopic (MRS) imaging, combined with brief inhalation of17O-isotope-enriched oxygen gas, has received increased interest. However, the low sensitivity of 17O MR signal has limited the potential of this technique. In this work, we introduced a novel double tuned 1H/17O head volume coil, in which the 1H coil is driven in quadrature mode and the 17O coil utilizes phased array approach.