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  Micromotors powered by enzyme catalysis

Dey, K. K., Zhao, X., Tansi, B. M., Méndez-Ortiz, J. W., Córdova-Figueroa, U. M., Golestanian, R., et al. (2015). Micromotors powered by enzyme catalysis. Nano Letters, 15(12), 8311-8315. doi:10.1021/acs.nanolett.5b03935.

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Dey, K. K., Autor
Zhao, X., Autor
Tansi, B. M., Autor
Méndez-Ortiz, J. W., Autor
Córdova-Figueroa, U. M., Autor
Golestanian, R.1, Autor           
Sen, A., Autor
Affiliations:
1Department of Living Matter Physics, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society, ou_2570692              

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 Zusammenfassung: Active biocompatible systems are of great current interest for their possible applications in drug or antidote delivery at specific locations. Herein, we report the synthesis and study of self-propelled microparticles powered by enzymatic reactions and their directed movement in substrate concentration gradient. Polystyrene microparticles were functionalized with the enzymes urease and catalase using a biotin-streptavidin linkage procedure. The motion of the enzyme-coated particles was studied in the presence of the respective substrates, using optical microscopy and dynamic light scattering analysis. The diffusion of the particles was found to increase in a substrate concentration dependent manner. The directed chemotactic movement of these enzyme-powered motors up the substrate gradient was studied using three-inlet microfluidic channel architecture. © 2015 American Chemical Society.

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Sprache(n): eng - English
 Datum: 2015-11-20
 Publikationsstatus: Erschienen
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 Ort, Verlag, Ausgabe: -
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 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1021/acs.nanolett.5b03935
BibTex Citekey: Dey2015
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Titel: Nano Letters
Genre der Quelle: Zeitschrift
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Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 15 (12) Artikelnummer: - Start- / Endseite: 8311 - 8315 Identifikator: -