English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
 Local TagsRelease HistoryDetailsSummary
  Chapter Ten - A Protocol for Large-Scale Proteomic Analysis of Microdissected Formalin Fixed and Paraffin Embedded Tissue

Ostasiewicz, P., & Wisniewski, J. R. (2017). Chapter Ten - A Protocol for Large-Scale Proteomic Analysis of Microdissected Formalin Fixed and Paraffin Embedded Tissue. In A. K. Shukla (Ed.), Proteomics in Biology, Part A (pp. 159-176). Cambridge: Academic Press. doi:10.1016/bs.mie.2016.09.017.

Item is

 

show all hide all

Basic

show hide
Item Permalink: https://hdl.handle.net/21.11116/0000-0001-6E9F-2 Version Permalink: https://hdl.handle.net/21.11116/0000-0001-711C-1
Genre: Book Chapter

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Ostasiewicz, P.1, Author
Wisniewski, J. R.2, Author           
Affiliations:
1external, ou_persistent22              
2Mann, Matthias / Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565159              

Content

show
hide
Free keywords: MASS-SPECTROMETRY; PROTEIN EXTRACTION; BREAST-CANCER; TUMOR-MARKERS; IDENTIFICATION; SHOTGUN; SAMPLES; BIOMARKERS; PROSTATE; FFPEBiochemistry & Molecular Biology;
 Abstract: Extensive use of biomarkers in diagnostic and therapeutic procedures is probably the hallmark of future medicine. Biomarkers can be of different chemical nature-most frequently DNA, RNA, and proteins are considered as molecules of interest. As the most rational approach appears analysis of proteins, because these are the "effector" molecules directly involved for cell homeostasis. There is no commonly accepted standard procedure in proteomic-based biomarker search. In this chapter, we described a protocol for proteomic analysis of formalin-fixed and paraffin-embedded tissue, which has been proven to be highly effective for proteomics-based biomarker discovery.

Details

show
hide
Language(s): eng - English
 Dates: 2016-12-012017
 Publication Status: Issued
 Pages: 18
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: ISI: 000403543200011
DOI: 10.1016/bs.mie.2016.09.017
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Proteomics in Biology, Part A
  Alternative Title : Methods Enzymol.
  Alternative Title : METHOD ENZYMOL
Source Genre: Book
 Creator(s):
Shukla, Arun K., Editor
Affiliations:
-
Publ. Info: Cambridge : Academic Press
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 159 - 176 Identifier: ISSN: 0076-6879
ISBN: 978-0-12-810534-4; 978-0-12-809742-7

Source 2

show
hide
Title: Methods in Enzymology
  Alternative Title : METHOD ENZYMOL
  Alternative Title : Methods Enzymol.
Source Genre: Series
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 585 Sequence Number: - Start / End Page: - Identifier: ISSN: 0076-6879